One of the technical challenges in spatial control is that existing ligand-based methods may not be optimal for localized stimulation. corresponding author upon request. Abstract During bone remodelling, osteoclasts induce chemotaxis of osteoblasts and yet maintain spatial segregation. We show that osteoclasts express the repulsive guidance factor Semaphorin 4D and induce contact inhibition of locomotion … Continue reading One of the technical challenges in spatial control is that existing ligand-based methods may not be optimal for localized stimulation